A Polygenic Mouse Model of Psoriasiform Skin Disease in CD18-Deficient Mice

    Daniel C. Bullard, Karin Scharffetter‐­Kochanek, Mark J. McArthur … Arthur L. Beaudet
    Studysummary This study found that homozygous mutant mice with a hypomorphic CD18 mutation developed a chronic inflammatory skin disease resembling human psoriasis, potentially implicating additional genetic factors in disease susceptibility.
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    Research cited in this study 1

    1. Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools Medical Entomology and Zoology · 1994

    Related research 1

    1. Role of Regulatory T Cells in Psoriasis Pathogenesis and Treatment British Journal of Dermatology · 2020