Updates in Therapeutics for Folliculitis Decalvans: A Systematic Review with Evidence-Based Analysis

August 2018 in “ Journal of the American Academy of Dermatology ”

Pooja H. Rambhia, Rosalynn R.Z. Conic, Aizuri Murad, Natasha Atanaskova-Mesinkovska, Melissa Piliang, Wilma F. Bergfeld

folliculitis decalvans clindamycin rifampicin isotretinoin photodynamic therapy hyperlipidemia Accutane PDT

Studysummary This study reported that a 10-week course of clindamycin and rifampicin was commonly used for treating folliculitis decalvans but the evidence on its efficacy remains inconclusive due to the low quality of available studies.

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Folliculitis Decalvans: Effectiveness of Therapies and Prognostic Factors in a Multicenter Series of 60 Patients with Long-Term Follow-Up

research Folliculitis Decalvans: Effectiveness of Therapies and Prognostic Factors in a Multicenter Series of 60 Patients with Long-Term Follow-Up

41 citations , June 2018 in “Journal of The American Academy of Dermatology”

This study examined the therapeutic response to folliculitis decalvans treatments among 60 patients and found that earlier disease onset was linked to more severe cases, while a combination of rifampicin, clindamycin, tetracyclines, and intralesional steroids was most effective in controlling symptoms.

research Isotretinoin Treatment for Folliculitis Decalvans: A Retrospective Case-Series Study

23 citations , January 2018 in “International Journal of Dermatology”

In this retrospective study, oral isotretinoin monotherapy effectively achieved remission in 82% of patients with folliculitis decalvans, with those receiving ≥0.4 mg/kg/day for ≥3 months experiencing better outcomes and less frequent relapse.

research Oral Isotretinoin as the Most Effective Treatment in Folliculitis Decalvans: A Retrospective Comparison of Different Treatment Regimens in 28 Patients

37 citations , February 2015 in “Journal of the European Academy of Dermatology and Venereology”

This study found that among patients with folliculitis decalvans, treatment with isotretinoin achieved the highest rate of stable remission compared to antibiotic regimens like clindamycin and rifampicin.

research Folliculitis Decalvans: A Multicenter Review of 82 Patients

68 citations , February 2015 in “Journal of the European Academy of Dermatology and Venereology”

This study found that severe folliculitis decalvans was associated with its onset before age 25 and the presence of pustules, while tetracyclines and clindamycin plus rifampicin were effective treatments.

research Retrospective Review of Folliculitis Decalvans in 23 Patients with Course and Treatment Analysis of Long-Standing Cases

43 citations , January 2015 in “Journal of Cutaneous Medicine and Surgery”

This study found that most patients with folliculitis decalvans showed improvement and remission with oral antibiotics, although some experienced relapses and required prolonged treatment.

research Folliculitis Decalvans Including Tufted Folliculitis: Clinical, Histological, and Therapeutic Findings

226 citations , February 1999 in “British Journal of Dermatology”

This study reported that a treatment regimen of oral rifampicin and clindamycin for 10 weeks effectively managed folliculitis decalvans, with most patients experiencing no recurrence after one or multiple courses.