A Case of Telogen Effluvium Associated with Drug-Induced Hyperprolactinemia

January 2020 in “ Nihon rinsho hifukaikai zasshi ”

Kaori Nonogaki, Rie Ueki

telogen effluvium hyperprolactinemia olanzapine valproic acid trazodone risperidone hair follicles resting phase serum prolactin PRL hair shedding hair loss hair volume

Studysummary This case study observed that discontinuing risperidone reduced elevated prolactin levels and improved hair thinning in a 77-year-old woman, suggesting risperidone-associated telogen effluvium as a consideration in similar cases.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on jstage.jst.go.jp →

Discuss this study in the Community →

Research cited in this study

5 / 5 results

research Valproate: Its Effects on Hair

11 citations , January 2018 in “International journal of trichology”

This article reviews valproate's impact on hair health, reporting both hair loss linked with oral use and early signs of hair regeneration from topical applications, without presenting new clinical results.

research Drugs and Hair Loss: Mechanisms and Clinical Implications

54 citations , September 2012 in “Dermatologic Clinics”

This review discusses possible medication-induced hair loss and the need to exclude other confounding factors like stress and illness; it reports no new clinical findings and emphasizes careful assessment before attributing hair loss to medications.

research Hair Loss and Hyperprolactinemia in Women

19 citations , January 2012 in “Dermato-endocrinology”

This study suggests that moderate elevated prolactin levels are unlikely to cause significant hair loss in women, but still warrant further diagnostic investigation to rule out a prolactin-producing pituitary tumor.

research Mind the Gender Gap: Does Prolactin Exert Gender and Site-Specific Effects on the Human Hair Follicle?

36 citations , November 2009 in “Journal of Investigative Dermatology”

This study suggests that prolactin has complex, gender- and location-dependent effects on human hair follicles, promoting hair growth in female frontotemporal scalp areas while inhibiting it in male occipital regions.

Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice

research Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice

73 citations , June 2001 in “Endocrinology”

In this study, researchers found that disrupting the PRL gene in mice led to earlier hair molting, especially in females, suggesting that PRL inhibits murine hair cycle events.