From Hair to Colon: Hair Follicle-Derived MSCs Alleviate Pyroptosis in DSS-Induced Ulcerative Colitis by Releasing Exosomes in a Paracrine Manner

    Yuan Chang, Yichi Zhang, Yanan Jiang … S. Jin
    Studysummary This study found that hair follicle-derived mesenchymal stem cells can alleviate pyroptosis and improve ulcerative colitis symptoms in mice, suggesting potential new treatments for the condition.
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    Research cited in this study 6

    1. ECM1 Modified HF-MSCs Targeting HSC Attenuate Liver Cirrhosis by Inhibiting the TGF-β/Smad Signaling Pathway Cell Death Discovery · 2022
    2. Hair Follicle-Derived Mesenchymal Stem Cells Decrease Alopecia Areata Mouse Hair Loss and Reduce Inflammation Around the Hair Follicle Stem Cell Research & Therapy · 2021
    3. From Hair to Pancreas: Transplanted Hair Follicle Mesenchymal Stem Cells Express Pancreatic Progenitor Cell Markers in a Rat Model of Acute Pancreatitis PubMed · 2021
    4. In Vitro Characterization of Human Hair Follicle Dermal Sheath Mesenchymal Stromal Cells and Their Potential in Enhancing Diabetic Wound Healing Cytotherapy · 2015
    5. Stem Cells and Alopecia: A Review of Pathogenesis British Journal of Dermatology · 2012
    6. Clonal Multipotency and Effect of Long-Term In Vitro Expansion on Differentiation Potential of Human Hair Follicle Derived Mesenchymal Stem Cells Stem Cell Research · 2011