Exploring imputation performance of phenotype-associated SNPs for forensic prediction models

    July 2026 in “ Scientific Reports ”
    Zehra Köksal, Andreas Tillmar
    Studysummary This study highlights the importance of imputation performance studies for phenotype-associated SNPs in forensics, showing that imputation improves phenotype prediction despite higher error rates for phenotypic SNPs compared to random SNPs.
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    Research cited in this study 7

    1. Recent Advances in Forensic DNA Phenotyping of Appearance, Ancestry, and Age Forensic Science International Genetics · 2023
    2. Exploring the Possibility of Predicting Human Head Hair Greying from DNA Using Whole-Exome and Targeted NGS Data BMC Genomics · 2020
    3. Genome-Wide Association Meta-Analysis of Individuals of European Ancestry Identifies New Loci Explaining a Substantial Fraction of Hair Color Variation and Heritability Nature Genetics · 2018
    4. Genetic Prediction of Male Pattern Baldness PLoS Genetics · 2017
    5. Prediction of Male-Pattern Baldness from Genotypes European Journal of Human Genetics · 2015
    6. Evaluation of the Predictive Capacity of DNA Variants Associated with Straight Hair in Europeans Forensic Science International: Genetics · 2015
    7. Evaluation of DNA Variants Associated with Androgenetic Alopecia and Their Potential to Predict Male Pattern Baldness PLOS ONE · 2015