Randomized Study to Evaluate the Efficacy of Platelet-Rich Plasma, Intralesional Triamcinolone Acetonide, and Intralesional Normal Saline in Moderate to Severe Alopecia Areata

    Manish Kumar, P.V. Krishnam Raju, B Gayatri Devi, Krishna Gopal, T Rao
    TLDR Intralesional triamcinolone acetonide is more effective but has a higher relapse rate than platelet-rich plasma for treating alopecia areata.
    This study compared the efficacy of platelet-rich plasma (PRP), intralesional triamcinolone acetonide (ILS), and intralesional normal saline (NS) in treating moderate to severe alopecia areata (AA) in 75 patients. The ILS group showed the highest improvement in hair regrowth with a 63.15% reduction in SALT score, followed by the PRP group with a 37.51% reduction. ILS also had a faster response within 4 weeks compared to PRP's 8-12 weeks. However, the ILS group had a higher relapse rate (21.7%) compared to the PRP group (4.1%). Both treatments were safe with no significant adverse effects.
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      community Do Platelet-rich plasma, PRP work?

      in Research/Science  12 upvotes 2 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 11 months ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Microneedling versus Platelet-Rich Plasma

      in Research/Science  10 upvotes 3 days ago
      Microneedling and Platelet-Rich Plasma (PRP) are equally effective for treating androgenetic alopecia, with no additional benefits from PRP over microneedling. Both treatments are safe and well-tolerated.

      community Why can't you drink caffeine after PRP?

      in Treatment  10 upvotes 3 years ago
      The conversation discusses avoiding caffeine after Platelet-Rich Plasma (PRP) treatment for hair loss because caffeine is a vasoconstrictor, which can reduce blood flow and hinder the healing process that PRP aims to promote.

      community I just made my own PRP - DIY PRP

      in Research/Science  552 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

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