Efficacy and Tolerability of HDMHG0401-10 in Patients with Androgenetic Alopecia: A Randomized Double-Blind Placebo-Controlled Trial

January 2005 in “ Translational and Clinical Pharmacology ”

Seoung-Ho Lee

HDMHG0401-10 androgenetic alopecia placebo hair loss hair count hair growth AGA

TLDR HDMHG0401-10 improves hair loss in men with androgenetic alopecia and has no major side effects.

This document is a summary of a study titled "Efficacy and tolerability of HDMHG0401-10 in Patients with Androgenetic Alopecia-A Randomized Double-blind Placebo-controlled Trial." The study aimed to determine if a new topical treatment called HDMHG0401-10 is effective in improving hair loss in patients with androgenetic alopecia (AGA). The study involved 41 men with AGA who were treated with either HDMHG0401-10 or a placebo for 24 weeks. The results showed that after 24 weeks of therapy, the HDMHG0401-10 treatment resulted in a significant improvement in total hair count and was significantly superior to the placebo in terms of hair loss count. There was no significant difference in hair growth ratings between the two groups. The treatment was generally well tolerated, and no major side effects were observed. In conclusion, the study confirmed the efficacy of HDMHG0401-10 in treating AGA in men.

View this study on kci.go.kr →

Discuss this study in the Community →

Related Research

15 / 15 results

research Efficacy and Safety of Baricitinib in Adults with Alopecia Areata: Phase 3 Results from a Randomized Controlled Trial (BRAVE-AA1)

3 citations, September 2021 in “Journal of Investigative Dermatology”

Baricitinib was more effective than a placebo in regrowing hair in adults with alopecia areata after 36 weeks.

Comment on 'The Effect of Platelet-Rich Plasma on Female Androgenetic Alopecia: A Randomized Controlled Trial': Phototrichogram Analysis

research Comment on 'The Effect of Platelet-Rich Plasma on Female Androgenetic Alopecia: A Randomized Controlled Trial': Phototrichogram Analysis

February 2021 in “Journal of The American Academy of Dermatology”

Platelet-rich plasma therapy's effectiveness for female hair loss needs more accurate data and further examination.

research A Randomized, Double-Blind, Placebo-Controlled, Split Patch Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

July 2018 in “International Journal of Research in Medical Sciences”

Platelet rich plasma was slightly more effective than no treatment for hair loss in alopecia areata patients.

A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia

research A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia

43 citations, July 2018 in “Journal of The European Academy of Dermatology and Venereology”

Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.

Efficacy and Safety of Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Self-Comparison, Sham Device-Controlled Trial

research Efficacy and Safety of Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Self-Comparison, Sham Device-Controlled Trial

31 citations, June 2018 in “Dermatologic Surgery”

Low-level light therapy safely improves hair coverage, thickness, and count in androgenetic alopecia patients.

research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis

54 citations, May 2018 in “Journal of The European Academy of Dermatology and Venereology”

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

A Proprietary Herbal Extract Against Hair Loss in Androgenetic Alopecia and Telogen Effluvium: A Placebo-Controlled, Single-Blind, Clinical-Instrumental Study

research A Proprietary Herbal Extract Against Hair Loss in Androgenetic Alopecia and Telogen Effluvium: A Placebo-Controlled, Single-Blind, Clinical-Instrumental Study

1 citations, January 2018 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)”

The herbal extract was found to effectively reduce and prevent hair loss without any side effects.

research Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia

3 citations, May 2017 in “Dermatologic Surgery”

PRP may help treat female hair loss, but more research needed.

research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis

178 citations, April 2017 in “Journal of The American Academy of Dermatology”

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations, April 2016 in “Dermatologic Surgery”

PRP treatment helps hair growth and density in androgenetic alopecia patients.

A Single-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Investigate the Efficacy and Safety of Minoxidil Topical Foam in Frontotemporal and Vertex Androgenetic Alopecia in Men

research A Single-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Investigate the Efficacy and Safety of Minoxidil Topical Foam in Frontotemporal and Vertex Androgenetic Alopecia in Men

19 citations, January 2015 in “Skin Pharmacology and Physiology”

Minoxidil foam effectively promotes hair growth and reduces hair loss in men.

research Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Multicenter Trial

106 citations, April 2013 in “Dermatologic Surgery”

Low-level light therapy safely improves hair growth and thickness for androgenetic alopecia.

research Alefacept for Severe Alopecia Areata: A Randomized, Double-Blind, Placebo-Controlled Study

3 citations, January 2011 in “Yearbook of Dermatology and Dermatologic Surgery”

research Randomized Clinical Trial Comparing 5% and 1% Topical Minoxidil for the Treatment of Androgenetic Alopecia in Japanese Men

29 citations, July 2009 in “Journal of Dermatology”

5% minoxidil works better for hair growth than 1% minoxidil.

research Efficacy and Tolerability of Finasteride 1 mg in Men Aged 41 to 60 Years with Male Pattern Hair Loss

22 citations, April 2003 in “PubMed”

Finasteride 1 mg significantly improves hair growth in men aged 41 to 60 with male pattern hair loss.