TLDR Sulfated fucans promote hair growth in mice by speeding up the growth phase and delaying the rest phase.
The study investigated the effects of sulfated fucans on the hair growth cycle in mice. Five days after hair removal, hair follicles in both the sulfated fucans and minoxidil groups were in anagen IV, while the control group was in anagen III. VEGF and HGF were present in the treated groups but not in the control. Eighteen days post-depilation, hair follicles in the treated groups were mostly in anagen VI, whereas the control group was in catagen, with no VEGF or HGF detected in any group. The results suggested that sulfated fucans promoted hair growth by advancing the hair follicle to anagen IV and delaying the transition to catagen, potentially due to the effects of VEGF and HGF.
3 citations
,
March 2015 in “Biomolecules & Therapeutics” Phospholipids from pig lungs can significantly promote hair growth.
1 citations
,
January 2015 in “Genetics and Molecular Research” Stopping S100A3 activity slows down hair growth in mice.
30 citations
,
October 2013 in “BMC dermatology” VEGF gel increases hair growth but may have potential toxicity.
5 citations
,
January 2013 in “Cells Tissues Organs” Activin B helps start and grow hair follicles in mice.
88 citations
,
June 2011 in “Journal of Dermatological Science” Minoxidil helps hair growth by activating the β-catenin pathway.
January 2008 in “Acta Anatomica Sinica”
25 citations
,
July 2004 in “Journal of Investigative Dermatology” Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.
January 2003 in “Journal of Clinical Dermatology”
520 citations
,
February 2001 in “Journal of Clinical Investigation” VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
23 citations
,
May 1998 in “Journal of Dermatological Science” Insulin or IGF-I is needed for hair growth in newborn mice, while minoxidil helps adult mouse hair grow, suggesting a way to study human hair loss.
154 citations
,
October 1996 in “Proceedings of the National Academy of Sciences of the United States of America” Estrogen affects hair growth and skin cell multiplication.