Effects of Nano-cerium Oxide on the Levels of DHT, TGF-β, and IGF-1 in the Local Skin of AGA Model Mice and Efficacy Observation

January 2025 in “ Journal of Contemporary Medical Practice ”

Andy Dong, Guohui Zhang

The study investigates the effects of nano-cerium oxide on androgenetic alopecia (AGA) in mice. C57BL/6 mice were divided into five groups, including a nano-cerium oxide group, and treated to establish an AGA model. The results showed that nano-cerium oxide increased the ratio of terminal hairs to vellus hairs, elevated IGF-1 protein expression, and decreased TGF-β and DHT levels in the skin. These findings suggest that nano-cerium oxide may help alleviate AGA, providing a basis for developing new treatments for this condition.

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