Clinical Effects of Follicle Unit Extraction and Transplantation Combined with Topical Recombinant Bovine Basic Fibroblast Growth Factor and Minoxidil in the Treatment of Secondary Cicatricial Alopecia

August 2021 in “ Chinese journal of burns ”

Qingwei Yang, P. Xue, Dou Wenjie, Xiaohui Fan, Bo Song

follicle unit extraction recombinant bovine basic fibroblast growth factor minoxidil secondary cicatricial alopecia hair transplantation FUE rb-bFGF Rogaine

TLDR Combining FUE with rb-bFGF and minoxidil is more effective and has fewer side effects than FUE alone for treating hair loss.

The study investigated the effects of combining follicle unit extraction (FUE) transplantation with recombinant bovine basic fibroblast growth factor (rb-bFGF) gel and minoxidil tincture in treating secondary cicatricial alopecia. It involved 100 patients, split into two groups of 50 each: one receiving only FUE and the other receiving FUE with rb-bFGF and minoxidil. Results showed that the combination treatment significantly reduced hair loss rates at 3 and 6 months post-surgery and improved hair survival rates and patient satisfaction at 12 months compared to FUE alone. The satisfaction rate was 94% in the combination group versus 74% in the FUE alone group. Additionally, the combination treatment resulted in fewer adverse effects, particularly a lower incidence of scarring at the donor site. Overall, the combination of FUE with rb-bFGF and minoxidil was more effective and had fewer side effects than FUE alone for treating cicatricial alopecia.

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community "Unlimited" hair follicles for HT?

in Research/Science 34 upvotes 3 years ago

Hair loss discussion mentions Verterporfin for scar-free healing and hair follicle regeneration. Human study expected within 2 years.

community Verteporfin and Microneedling

in Treatments 6 months ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

26 upvotes 10 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Holy shit. Verteporfin may actually be the cure

in Research/Science 1016 upvotes 1 year ago

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community 6 months after FUE. I know hair is longer and different light, but the resultat is amazing so far. Confidence is skyhigh!

in Transplants 3 years ago

User had successful FUE hair transplant with 3500 grafts, costing 3900 euros at Novohair in Berlin, gaining confidence. User lost hair due to chemo, family history of hair loss at 40-50 years old.

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