Early Trichoscopic Changes of Minoxidil Therapy in Male Pattern Hair Loss: A Prospective Cohort Study

December 2025 in “ Journal of Pharmacy And Bioallied Sciences ”

Neha Shukla, Chandra Shekhar Jaiswal, Jyoti Nagwanshi, Dileep Dandotiya, Ranjana Sharma

minoxidil male pattern hair loss trichoscopy scalp dryness increased shedding Rogaine

TLDR Trichoscopy effectively shows early positive effects of minoxidil in male pattern hair loss, improving patient satisfaction.

This prospective cohort study of 200 male patients aged 18-40 years with male pattern hair loss (MPHL) assessed early trichoscopic changes during minoxidil therapy. Significant improvements were observed, especially in the frontal scalp area, after 2 months of treatment. Key findings included an increase in hair count and anisotrichosis, and a reduction in peripilar sign and yellow dots. Patient satisfaction was high, with 70% reporting satisfaction with the therapy. The study underscores the value of trichoscopy in monitoring early therapeutic effects, which can improve patient compliance and satisfaction.

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