Dutasteride nanocapsules for hair follicle targeting: Effect of chitosan-coating and physical stimulus
May 2020
in “International Journal of Biological Macromolecules”
TLDR Chitosan-coated dutasteride nanocapsules improve hair treatment, and physical stimulation boosts effectiveness.
The study investigated the use of dutasteride nanocapsules for targeted hair follicle treatment. Chitosan-coating was found to enhance drug delivery and provide controlled drug release, while physical stimulus significantly improved nanoparticles accumulation into the follicular shaft. The study demonstrated that dutasteride nanocapsules can target the follicular casts, and a simple physical stimulation can enhance the drug amount accumulated.
View this study on sciencedirect.com →
Cited in this study
research The efficacy and safety of dutasteride compared with finasteride in treating men with androgenetic alopecia: a systematic review and meta-analysis
Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.
research Prospective randomized study of sexual function in men taking dutasteride for the treatment of androgenetic alopecia
Dutasteride safely treats hair loss without harming sexual function.
research Preparation and characterization of dutasteride-loaded nanostructured lipid carriers coated with stearic acid-chitosan oligomer for topical delivery
The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.
research Dutasteride in Androgenetic Alopecia: An Update
Dutasteride is becoming a popular hair loss treatment, proving more effective than finasteride with similar side effects.
research Solid effervescent formulations as new approach for topical minoxidil delivery
Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
research Chitosan nanoparticles for targeting and sustaining minoxidil sulphate delivery to hair follicles
Chitosan nanoparticles improve minoxidil delivery to hair follicles for better alopecia treatment.
research Iontophoresis-Targeted, Follicular Delivery of Minoxidil Sulfate for the Treatment of Alopecia
Iontophoresis improves minoxidil delivery for alopecia treatment.
Related
research Dutasteride nanocapsules for hair follicle targeting: Effect of chitosan-coating and physical stimulus
Chitosan-coated dutasteride nanocapsules improve hair treatment, and physical stimulation boosts effectiveness.