Keys to the Diagnosis of Hair Shaft Disorders: Part II

February 2022 in “ Actas dermo-sifiliográficas/Actas dermo-sifiliográficas ”

A. Giacaman, Juan Ferrando

hair shaft disorders genetic mutations environmental factors trichoscopy topical minoxidil Rogaine

TLDR Hair shaft disorders, often due to genetics or environment, lack specific treatments but can be managed with gentle hair care and may improve with age or topical treatments.

This review discusses various hair shaft disorders caused by genetic mutations or environmental factors, classifying them based on hair fragility. Diagnosis involves medical history, hair examination, and trichoscopy. Specific treatments are not available, but general care practices are recommended. Some disorders improve with puberty, while others may respond to treatments like topical minoxidil. The review emphasizes the importance of multidisciplinary evaluation and genetic counseling for hereditary conditions, and highlights the role of detailed clinical examination and advanced diagnostic techniques in accurately diagnosing these disorders.

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Research cited in this study

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research Prognosis and Management of Congenital Hair Shaft Disorders with Fragility—Part I

33 citations , June 2016 in “Pediatric Dermatology”

Some congenital hair disorders improve in childhood or with treatments like minoxidil and retinoids, while others like Netherton syndrome and trichothiodystrophy have a poor prognosis.

research Prognosis and Management of Congenital Hair Shaft Disorders Without Fragility—Part II

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Some congenital hair disorders improve with age and can be managed with treatments like minoxidil, retinoids, supplements, and gentle hair care, but there's no cure.

research Hair Follicle Miniaturization in a Woolly Hair Nevus

6 citations , February 2016 in “American Journal of Dermatopathology”

The boy with woolly hair nevus had thinner hair and abnormal hair follicles, which improved with treatment but worsened when treatment stopped.

research Whisker Hair (Acquired Progressive Kinking of the Hair): An Indication for Finasteride 1 mg?

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Taking 1 mg of finasteride daily could potentially treat rare hair conditions like Acquired Progressive Kinking of the Hair and whisker hair.

research Hair Shafts in Trichoscopy

86 citations , October 2013 in “Dermatologic Clinics”

Trichoscopy is a useful non-invasive method for diagnosing different hair loss conditions.

research Clinical Effects of Non-Ablative and Ablative Fractional Lasers on Various Hair Disorders: A Case Series of 17 Patients

46 citations , March 2013 in “Journal of Cosmetic and Laser Therapy”

Non-ablative and ablative fractional lasers helped hair growth in some cases without major side effects, but didn't work for all hair disorders.

research Acquired Progressive Kinking of Hair Affecting the Scalp and Eyelashes in an Adult Woman

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A woman developed rare, unexplained curly hair on her scalp and eyelashes.

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19 citations , March 1988 in “International Journal of Dermatology”

Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.

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