Cyclic Dynamics of Hair Follicles and the Effect of Minoxidil on the Bald Scalps of Stumptailed Macaques

    June 1985 in “ American Journal of Dermatopathology ”
    Hideo Uno, Adrienne Cappas, Carl A. Schlagel
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    TLDR Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.
    This 1985 scientific paper discusses the cyclic changes that hair follicles undergo throughout life and the effect of minoxidil on bald scalps of stumptailed macaques. The study found that minoxidil can lead to the growth of longer and thicker hairs in bald scalps of stumptailed macaques. The study also revealed that minoxidil induces enlargement of regrowing follicles during early anagen phases by enhancing the proliferation of follicular cells in the secondary bud, producing a larger follicle than that of the previous cycle. The study suggests that treatment in early stages of baldness should be more effective than treatment at advanced stages.
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