Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism

    Yusuf Şahin, Fahri Bayram, Fahrettin Kelestimur, Iptisam Ipek Muderris
    Studysummary In this study, both cyproterone acetate-estrogen combination (Diane®) and finasteride were effective in reducing hirsutism, but Diane® showed greater long-term efficacy and cost-effectiveness.
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    Research cited in this study 12

    1. Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up Fertility and Sterility · 1996
    2. Clinical Review 73: Medical Treatment of Androgen-Dependent Hirsutism ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1995
    3. Clinical and Endocrine Effects of Finasteride, a 5α-Reductase Inhibitor, in Women with Idiopathic Hirsutism Fertility and Sterility · 1995
    4. A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women The Journal of Clinical Endocrinology and Metabolism · 1995
    5. Clinical and Hormonal Effects of the 5 Alpha-Reductase Inhibitor Finasteride in Idiopathic Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1994
    6. Effects of Finasteride, a 5 Alpha-Reductase Inhibitor, on Circulating Androgens and Gonadotropin Secretion in Hirsute Women The Journal of Clinical Endocrinology and Metabolism · 1994
    7. Finasteride The New England Journal of Medicine · 1994
    8. Finasteride: The First 5α-Reductase Inhibitor Pharmacotherapy · 1993
    9. Finasteride: The First 5 Alpha-Reductase Inhibitor PubMed · 1993
    10. Cyproterone Acetate for Severe Hirsutism: Results of a Double-Blind Dose-Ranging Study Clinical endocrinology · 1991
    11. Pharmacology and Potential Use of Cyproterone Acetate Hormone and metabolic research · 1977
    12. Use of Cyproterone Acetate in the Treatment of Acne, Hirsutism, and Virilism Journal of Steroid Biochemistry · 1975

    Related research 7

    1. Finasteride Versus Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism International journal of gynaecology and obstetrics · 2004
    2. Medical Treatment Regimens of Hirsutism Reproductive biomedicine online · 2004
    3. Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism Fertility and Sterility · 2001
    4. Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism Fertility and Sterility · 2000
    5. Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism Journal of Endocrinological Investigation · 1998
    6. Androstanediolglucuronide: A Parameter for Peripheral Androgen Activity Before and During Therapy with Cyproterone Acetate European journal of endocrinology · 1991
    7. The Influence of Long-Term Treatment with Cyproterone Acetate or a Cyproterone Acetate-Ethinyl Estradiol Combination on Androgen Levels in Blood of Hirsute Women Journal of steroid biochemistry/Journal of Steroid Biochemistry · 1980