September 2025 in “PubMed” This review discusses recent advances in hair regeneration strategies, including mechanical stimulation and complementary therapies like MSC transplantation and platelet-rich plasma, and reports no new clinical results.
163 citations
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April 2019 in “Nature Communications” This study found that mechanical skin stretching can stimulate hair stem cell proliferation and hair regeneration by activating a complex pathway involving WNT, BMP-2, and M2 macrophages.
October 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that applying the right mechanical stretch to skin can activate hair stem cells and promote hair regeneration through a pathway involving WNT, BMP-2, and M2 macrophages.
60 citations
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July 2011 in “Stem Cells and Development” This review discusses recent findings on hair follicle morphogenesis and regeneration, focusing on molecular signals and stem cells, and suggests that understanding these processes may aid in developing new strategies for wound healing.
86 citations
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February 2012 in “Journal of Clinical Investigation” This review discusses recent advances in understanding hair follicle stem cell dynamics and interactions, but it reports no new experimental findings.