Biological characterization of cultured dermal papilla cells and hair follicle regeneration in vitro and in vivo
February 2006
in “Chinese Medical Journal”
TLDR Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.
This study from 2006 investigated the potential of dermal papilla cells (DPC) for hair follicle regeneration. The researchers found that the expression of certain cytokines in DPC was correlated with their ability to induce hair follicle regeneration. They also observed the formation of hair follicle-like structures in organotypic cultures of DPC and hair follicle epithelium cells, which were implanted into nude mice. The study concluded that cultured DPC can induce hair follicle regeneration and sustain hair growth in vivo and in vitro.
View this study on journals.lww.com →
Cited in this study
research Reorganization of hair follicles in human skin organ culture induced by cultured human follicle-derived cells
Injected human hair follicle cells can create new, small hair follicles in skin cultures.
research Hair cycle and hair pigmentation: dynamic interactions and changes associated with aging
As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.
research Molecular Control of Epithelial–Mesenchymal Interactions During Hair Follicle Cycling
research Simple and rapid method to isolate and culture follicular papillae from human scalp hair follicles
Researchers developed a quick and easy way to get and grow cells from the base of human hair follicles.
research Role of hair papilla cells on induction and regeneration processes of hair follicles
Hair papilla cells can create and regenerate hair bulbs under the right conditions.
research DERMAL-EPIDERMAL INTERACTIONS
Related
research Biological characterization of cultured dermal papilla cells and hair follicle regeneration in vitro and in vivo
Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.
research [Hair follicle regeneration after implantation of hair follicle cells into subcutis of nude mice].
research Trans‐species hair growth induction by human hair follicle dermal papillae
Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.