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GlossaryOrgan Culture

Organ culture, also known as organotypic culture, is a laboratory technique where whole organs or tissue sections are maintained in a controlled environment outside of the organism. This method allows researchers to study the function, development, and pathology of the organ in a setting that closely mimics its natural state, providing valuable insights into biological processes and potential treatments for diseases.

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research Disturbed Keratinocyte Differentiation in Transgenic Mice and Organotypic Keratinocyte Cultures Due to Spermidine/Spermine N1-Acetyltransferase Overexpression

37 citations, February 2005 in “Journal of Investigative Dermatology”

Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.

Effects of 1α,25-Dihydroxy-Vitamin D3 and Calcipotriol on Organotypic Cultures of Outer Root Sheath Cells: A Potential Model to Evaluate Antipsoriatic Drugs

research Effects of 1α,25-Dihydroxy-Vitamin D3 and Calcipotriol on Organotypic Cultures of Outer Root Sheath Cells: A Potential Model to Evaluate Antipsoriatic Drugs

10 citations, October 1993 in “Archives of dermatological research”

Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.

Effect of Low-Level Laser Therapy on Hair Cell Regeneration Following Gentamicin-Induced Ototoxicity in Postnatal Organotypic Culture of Rat Cochlea

research Effect of Low-Level Laser Therapy on Hair Cell Regeneration Following Gentamicin-Induced Ototoxicity in Postnatal Organotypic Culture of Rat Cochlea

1 citations, February 2010 in “Proceedings of SPIE”

Low level laser therapy may help regenerate hair cells in the ear after damage from gentamicin.

research Biological Characterization of Cultured Dermal Papilla Cells and Hair Follicle Regeneration In Vitro and In Vivo

24 citations, February 2006 in “Chinese Medical Journal”

Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.

research Hair-Follicle Dermal Papilla and Sheath Fibroblasts Provide a Supportive Microenvironment for Human Skin Regeneration

3 citations, May 2017 in “British journal of dermatology/British journal of dermatology, Supplement”

Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.

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