Biochemical Evidence That Small Proline-Rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes

    May 1998 in “ Journal of biological chemistry/˜The œJournal of biological chemistry ”
    Peter M. Steinert, Tonja Kartašova, Lyuben N. Marekov
    Studysummary This study found that small proline-rich proteins modify the biomechanical properties of cornified cell envelopes in rodent forestomachs, potentially affecting the tissue's ability to withstand mechanical stress.
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    Research cited in this study 8

    1. The Fate of Trichohyalin Journal of biological chemistry/˜The œJournal of biological chemistry · 1997
    2. Hair Keratinization in Health and Disease Dermatologic clinics · 1996
    3. Localization and Expression of Cornifin-α/SPRR1 in Mouse Epidermis, Anagen Follicles, and Skin Neoplasms Journal of Investigative Dermatology · 1996
    4. Trichohyalin: A Structural Protein of Hair, Tongue, Nail, and Epidermis ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    5. The Structure of Human Trichohyalin: Potential Multiple Roles as a Functional EF-Hand-Like Calcium-Binding Protein, a Cornified Cell Envelope Precursor, and an Intermediate Filament-Associated (Cross-Linking) Protein Journal of Biological Chemistry · 1993
    6. Analysis of the Sheep Trichohyalin Gene: Potential Structural and Calcium-Binding Roles of Trichohyalin in the Hair Follicle The Journal of Cell Biology · 1993
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    8. Structural Features of the Alpha-Type Filaments of the Inner Root Sheath Cells of the Guinea Pig Hair Follicle Biochemistry · 1978