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GlossaryLoricrin

protein crucial for skin's outermost layer integrity and resilience

Loricrin is a protein that plays a crucial role in the formation of the skin's outermost layer, the stratum corneum. It is a major component of the cornified cell envelope, which provides a barrier to protect against environmental damage and water loss. This protein is essential for maintaining the skin's integrity and resilience.

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research 25 Hydroxyvitamin D 1 Alpha-Hydroxylase Is Required for Optimal Epidermal Differentiation and Permeability Barrier Homeostasis

140 citations , April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology”

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

research Biochemical Evidence That Small Proline-Rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes

99 citations , May 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.

research Noggin Overexpression Inhibits Eyelid Opening by Altering Epidermal Apoptosis and Differentiation

65 citations , June 2003 in “EMBO journal”

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

research Organization and Expression of Hair Follicle Genes

48 citations , July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”

Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.

research Loss of Keratin 10 Is Accompanied by Increased Sebocyte Proliferation and Differentiation

36 citations , January 2004 in “European journal of cell biology”

Without keratin 10, there's more growth and development of oil-producing skin cells.

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