Efficacy of Bimatoprost in Treating Chemotherapy-Induced Milphosis: A Comprehensive Review of Randomized Controlled Trials

March 2025 in “ JAAD reviews. ”

Simonetta I. Gaumond, Peyton V. Warp, Rama Abdin, Joaquín J. Jiménez

bimatoprost chemotherapy-induced milphosis nonscalp alopecia Latisse

TLDR Bimatoprost effectively improves eyelashes in chemotherapy patients.

This review assesses the effectiveness of bimatoprost in treating chemotherapy-induced milphosis, focusing on three randomized controlled trials with 186 participants. Bimatoprost significantly improved eyelash length, thickness, and pigmentation, enhancing patient satisfaction. Although the treatment showed promise, limitations such as small sample sizes and short follow-up periods highlight the need for further research. Bimatoprost has a favorable safety profile, with mild adverse events reported, and may be considered by dermatologists and oncologists as part of supportive care for nonscalp alopecia in oncology patients.

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Research cited in this study

15 / 15 results

research From Eye Care to Hair Growth: Bimatoprost

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The review shows how to properly diagnose and treat the loss of eyebrow and eyelash hair.

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Madarosis (eyebrow and eyelash loss) significantly affects quality of life for breast cancer patients on taxane-based chemotherapy.

research Madarosis, Milphosis, Eyelash Trichomegaly, and Dermatochalasis: Conditions Affecting the Periocular Area

10 citations , February 2015 in “Clinics in Dermatology”

The document concludes that changes in eyelashes and eyelid skin can indicate various local and systemic diseases.

research Bimatoprost Versus Mometasone Furoate in the Treatment of Scalp Alopecia Areata: A Pilot Study

36 citations , January 2015 in “Dermatology”

Bimatoprost was found to be safer and more effective than mometasone furoate for treating scalp hair loss.

Long-Term Safety and Efficacy of Bimatoprost Solution 0.03% Application to the Eyelid Margin for the Treatment of Idiopathic and Chemotherapy-Induced Eyelash Hypotrichosis: A Randomized Controlled Trial

research Long-Term Safety and Efficacy of Bimatoprost Solution 0.03% Application to the Eyelid Margin for the Treatment of Idiopathic and Chemotherapy-Induced Eyelash Hypotrichosis: A Randomized Controlled Trial

38 citations , October 2014 in “British journal of dermatology/British journal of dermatology, Supplement”

Bimatoprost solution is effective and safe for long-term use in treating eyelash thinning.

research Treatment of Chemotherapy-Induced Alopecia

64 citations , July 2011 in “Dermatologic Therapy”

Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.

research Enhancing the Growth of Natural Eyelashes: The Mechanism of Bimatoprost-Induced Eyelash Growth

69 citations , April 2010 in “Dermatologic Surgery”

Bimatoprost is a safe and effective treatment for making eyelashes longer, thicker, and darker.

research Management of Hypotrichosis of the Eyelashes: Focus on Bimatoprost

23 citations , April 2010 in “Clinical, cosmetic and investigational dermatology”

Bimatoprost ophthalmic solution 0.03% safely and effectively increases eyelash growth when applied to the upper eyelid.

research Characterization of an In Vivo Model for the Study of Eyelash Biology and Trichomegaly: Mouse Eyelash Morphology, Development, Growth Cycle, and Anagen Prolongation by Bimatoprost

35 citations , March 2010 in “British journal of dermatology/British journal of dermatology, Supplement”

The study showed that mouse eyelashes can be used to study eyelash growth and that bimatoprost makes them longer and more numerous.

research Instilled Bimatoprost Ophthalmic Solution in Patients with Eyelash Alopecia Areata

30 citations , August 2009 in “Journal of the American Academy of Dermatology”

Bimatoprost is safe but not effective for severe eyelash loss from alopecia areata, possibly helping those with less loss.

research Androgens and Hair Growth

209 citations , September 2008 in “Dermatologic Therapy”

Androgens can both increase and decrease hair growth in different parts of the body.

research Madarosis

33 citations , November 2006 in “Survey of Ophthalmology”

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

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7 citations , May 1979 in “Medical & biological engineering & computing”

The trichometer accurately measures hair growth and is easy to use.

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