TLDR There is no proven treatment for post-finasteride syndrome yet.
There is no definitive treatment for post-finasteride syndrome (PFS). However, studies suggest potential benefits from treatments such as allopregnanolone, trazodone, antipsychotic drugs, and hormonal therapies. Further research is required to confirm their efficacy.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” There is no proven treatment for post-finasteride syndrome yet.
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April 2018 in “Endocrine” PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
Allopregnanolone may help reduce inflammation and symptoms related to post-finasteride syndrome.
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August 2021 in “Biomedicine & Pharmacotherapy” 5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.
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February 2017 in “Clinical Drug Investigation” Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.