The Belgian Ten-Center Open Label Trial of Topical 2% Minoxidil Solution in Early Male Pattern Alopecia

In a 24-week open-label study conducted in Belgium, 149 male patients with early male pattern alopecia applied a 2% minoxidil solution twice daily. The study found statistically significant increases in hair counts from baseline to week 24. Nearly 47% of patients and 44% of investigators reported cosmetically acceptable moderate to dense hair growth. The treatment was generally safe, with no significant changes in vital signs or abnormal findings in cardiac assessments, although two patients withdrew due to dermatologic issues. The study confirmed the safety and efficacy of minoxidil for treating early male pattern alopecia.