Role of Both Azathioprine and Methotrexate in Management of Alopecia Areata: Review Article

October 2022 in “ The Egyptian Journal of Hospital Medicine ”

Abdalla Hasan Kandil, Hassan Senoussi Houssin Osman, Mohamed Ibrahim El Ghareeb

azathioprine methotrexate alopecia areata non-scarring hair loss

TLDR Methotrexate and azathioprine can help treat alopecia areata.

The review article assessed the roles of azathioprine and methotrexate in managing alopecia areata (AA), a prevalent form of non-scarring hair loss. The study concluded that both methotrexate and azathioprine could be effective as monotherapy or as adjunctive treatments for AA. The review involved a comprehensive search of literature from March 2010 to May 2021, focusing on English-language studies and excluding non-scientific documents.

View this study on ejhm.journals.ekb.eg →

Discuss this study in the Community →

Research cited in this study

5 / 5 results

research Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management

290 citations , August 2021 in “Clinical Reviews in Allergy & Immunology”

JAK inhibitors show promise for treating alopecia areata, but more research is needed.

research Alopecia Areata: A Review on Diagnosis, Immunological Etiopathogenesis, and Treatment Options

56 citations , January 2021 in “Clinical and Experimental Medicine”

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

research Co-Localization of Alopecia Areata and Lichen Planopilaris in a Patient Receiving Immunosuppressants: A Rare Case

1 citations , July 2020 in “Journal of cosmetic dermatology”

A woman on immunosuppressants developed two rare scalp conditions, which improved with specific treatments.

research Treatment of Alopecia Areata: An Australian Expert Consensus Statement

95 citations , November 2018 in “Australasian journal of dermatology”

Alopecia areata treatment varies, with no optimal method established yet.

research Efficacy and Safety of Methotrexate in Alopecia Areata

44 citations , August 2014 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.

Related Research

4 / 4 results

research Role of Both Azathioprine and Methotrexate in Management of Alopecia Areata: Review Article

October 2022 in “The Egyptian Journal of Hospital Medicine”

Methotrexate and azathioprine can help treat alopecia areata.

research Co-Localization of Alopecia Areata and Lichen Planopilaris in a Patient Receiving Immunosuppressants: A Rare Case

1 citations , July 2020 in “Journal of cosmetic dermatology”

A woman on immunosuppressants developed two rare scalp conditions, which improved with specific treatments.

research Alopecia Areata in 12-Year-Old Female Treated with Oral Azathioprine: A Case Report and Review

January 2019 in “Journal of Case Reports and Scientific Images”

Azathioprine may help treat Alopecia Areata.

research Methotrexate for the Treatment of Pediatric Alopecia Areata

22 citations , June 2017 in “Journal of dermatological treatment”

Methotrexate is generally safe and often effective for treating hair loss in children.