Antibacterial and Wound Healing Stimulant Nanofibrous Dressing Consisting of Soluplus and Soy Protein Isolate Loaded with Mupirocin

November 2024 in “ Scientific Reports ”

Maryam Jahani, Azadeh Asefnejad, Mastafa H. Al‐Musawi, Ahmed A. Mohammed, Basma Talib Al-Sudani, Maha Hameed Al-bahrani, Nada A. Kadhim, Mina Shahriari‐Khalaji, Hamideh Valizadeh, Fariborz Sharifianjazi, Morteza Mehrjoo, Ketevan Tavamaishvili, Mohamadreza Tavakoli

nanofibrous dressing Soluplus soy protein isolate mupirocin extracellular matrix cell adhesion human keratinocyte cells gram-positive bacteria gram-negative bacteria methicillin-resistant staphylococci wound healing antibacterial activity MRSA antibacterial wound dressing

Studysummary This study developed electrospun nanofibers containing mupirocin for wound treatment, reporting enhanced antibacterial activity, high water absorption, and accelerated wound healing in a rat model, suggesting potential use for severe skin injuries at risk of infection.

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