Bacterial Cellulose/Soybean Protein Isolate Composites with Promoted Inflammation Inhibition, Angiogenesis, and Hair Follicle Regeneration for Wound Healing

The study investigated the use of bacterial cellulose/soybean protein isolate composites for wound healing. The researchers prepared composites using beta-conglycinin (7S) and glycinin (11S) proteins obtained from soybean protein. The composites were found to promote fibroblast proliferation and collagen expression in vitro. In vivo experiments on rats showed that the composites facilitated wound healing, collagen deposition, angiogenesis, and hair follicle regeneration. The composites also reduced scar formation and inflammation. The composite with 11S protein showed better results compared to the one with 7S protein, possibly due to the larger amount of soybean protein released. The study suggests that these composites have potential as wound dressings.