Antiandrogen Therapy for Female-Pattern Hair Loss

January 2005 in “ NEJM Journal Watch ”

Neil H. Shear, Frcpc

female-pattern hair loss FPHL telogen effluvium topical minoxidil antiandrogens spironolactone cyproterone Rogaine

TLDR Antiandrogens like spironolactone can help treat female-pattern hair loss.

The document discussed female-pattern hair loss (FPHL), which could manifest as a diffuse reduction in hair density on the crown or increased telogen-hair shedding. Chronic shedding was noted as a characteristic of chronic telogen effluvium. Treatment options for FPHL at the time included topical minoxidil and antiandrogens like spironolactone and cyproterone.

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research Treatment of Female Pattern Hair Loss With Oral Antiandrogens

179 citations, March 2005 in “British Journal of Dermatology”

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

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6 / 1000+ results

community Diagnosed with female pattern hair loss as a male with recent aggressive loss. Preemptively mourning the only part of myself I’ve ever come close to loving. Lost all motivation to do anything with my life.

in Progress Pictures 271 upvotes 1 year ago

The conclusion of the conversation is that the user should consider using treatments such as finasteride, minoxidil, and RU58841 to potentially reverse their hair loss. Other suggestions include using hair loss concealers and maintaining a healthy diet.

community Got my DHT levels checked. 38 year old female. Still losing hair.

in Female 10 upvotes 6 months ago

A 38-year-old female is experiencing hair loss despite having almost undetectable DHT levels after using dutasteride. Suggestions include checking for PCOS, thyroid issues, adjusting diet, considering the impact of birth control, and trying treatments like tretinoin, redensyl, retinol, and minoxidil with derma stamping.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Spironolactine Update: 2 months (34, Female)

in Female 23 upvotes 7 years ago

A female user's experience using Spironolactone to treat Female Pattern Hair Loss (FPHL) and Androgenic Alopecia, as well as discussing the effectiveness of the drug at different dosages.

community For the ladies: Spironolactone for FPHL

in Female 12 upvotes 7 years ago

A 34 year old female with androgenic alopecia who has tried treatments such as Spironolactone, Desogen, Minoxidil and Finasteride in order to address her hair loss. It also details the experiences of other women taking Spironolactone for Female Pattern Hair Loss (FPHL).

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Topical Odorant Application of the Specific Olfactory Receptor OR2AT4 Agonist, Sandalore, Improves Telogen Effluvium-Associated Parameters

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Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect

research Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect

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Finasteride helps hair growth but stopping it causes faster hair loss.

research Hair Restoration Surgery: Follicular Unit Grafting

December 2016

Follicular unit grafting is a procedure used to treat hair loss, where small hair grafts are placed into the scalp, with future treatments likely to involve smaller incisions and cell-based therapies.

research Hair Disorders Associated With Anticancer Agents

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Some cancer treatments cause different types of hair loss, but scalp cooling can help prevent it.

research A New Strategy to Modulate Alopecia Using a Combination of Two Specific and Unique Ingredients

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A new hair loss treatment with two unique ingredients improved hair growth.

research Hair Loss in Women: Medical and Cosmetic Approaches to Increase Scalp Hair Fullness

75 citations, December 2011 in “British Journal of Dermatology”

Female pattern hair loss can be treated with medications, surgery, and cosmetic products, considering its psychological impact.

research An Overview of Female Pattern Hair Loss

2 citations, June 2011 in “Expert Review of Dermatology”

Female pattern hair loss involves thinning hair on crown and frontal scalp, diagnosed by hair ratio, and treated with minoxidil, antiandrogens, or hair transplantation.