Androgen Deprivation Therapy and Hormonal Status in Men with COVID-19

December 2022 in “ Urology Herald ”

А А Камалов, Dmitri Alexsandrovich Ohobotov, O. Yu. Nesterova, A. A. Strigunov, A. S. Tivtikyan

androgen deprivation therapy ADT androgens testosterone dihydrotestosterone

TLDR Hormonal status from androgen deprivation therapy may affect COVID-19 severity in men.

The document reviews literature on the relationship between androgen deprivation therapy (ADT) and COVID-19 severity in men, highlighting that different classes of ADT affect androgen levels differently, which is often overlooked in analyses. The review specifically targets studies where ADT has a unidirectional effect on male sex hormone concentrations and examines the connection between COVID-19 and androgens like testosterone and dihydrotestosterone. The findings suggest that hormonal status, influenced by ADT, may play a role in the severity of COVID-19 in men, necessitating further research to understand these dynamics fully.

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