Innovative Method of Alopecia Treatment Using Adipose-Derived Stromal Vascular Fraction Cells

June 2021 in “ Research Square (Research Square) ”

Kim Sj, Mi‐Hyun Kim, Lee Y, Lee J, Jae‐Hun Kim, Do-Hyung Kim, Do Yh, Choi Jw, Chung Si, Do Br

adipose-derived stromal vascular fraction cells SVF cells androgenetic alopecia AGA autologous SVF hair density keratin SVF hair loss hair thickness

TLDR Using fat-derived cells to treat hair loss increased hair density and thickness without side effects.

The study "Innovative Method of Alopecia Treatment by Using Adipose-derived Stromal Vascular Fraction (SVF) Cells" evaluated the efficacy of SVF cells in treating androgenetic alopecia (AGA). The study involved 9 patients aged 43-64 years (4 men, grade IV to V and 5 women, grade I to III) suffering from AGA. They were treated with a single injection of autologous SVF in the upper scalp. The results showed a significant increase in hair density after 3 and 6 months post-injection (P = 0.01 and P=0.009), and an increase in thickness at 6 months post-injection (P = 0.02). There was also a significant improvement in the score of keratin of the scalp on the treated side compared to the untreated side (p=0.032). No side effects were reported, confirming the safety and efficacy of the treatment.

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research A Randomized, Double-Blind, Vehicle-Controlled Clinical Study of Hair Regeneration Using Adipose-Derived Stem Cell Constituent Extract in Androgenetic Alopecia

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New treatment combining PRP and SVF increases hair density in 6-12 weeks for androgenetic alopecia patients.

research Stem Cell Therapy as a Novel Therapeutic Intervention for Resistant Cases of Alopecia Areata and Androgenetic Alopecia

39 citations , March 2018 in “Journal of Dermatological Treatment”

Stem cell therapy may help treat tough hair loss cases.

research Up-To-Date Clinical Trials of Hair Regeneration Using Conditioned Media of Adipose-Derived Stem Cells in Male and Female Pattern Hair Loss

30 citations , September 2017 in “Current stem cell research & therapy”

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research Androgenetic Alopecia: An Update Of Treatment Options

110 citations , August 2016 in “Drugs”

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research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

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Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

research Psychological Effect, Pathophysiology, and Management of Androgenetic Alopecia in Men

112 citations , October 2005 in “Mayo Clinic Proceedings”

Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.

research A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss

219 citations , April 2004 in “Journal of The American Academy of Dermatology”

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men

269 citations , September 2002 in “Journal of The American Academy of Dermatology”

5% minoxidil works better for hair growth and density, with minor irritation.

4 / 4 results

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research Treating Resistant Cases of Alopecia Universalis

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research Management of Autoimmune-Associated Alopecia Areata

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