The Most Recent Advances in Understanding and Managing Hidradenitis Suppurativa

    August 2020 in “ F1000Research
    Shanthi Narla, Alexis B. Lyons, Iltefat Hamzavi
    TLDR Better understanding and new treatments for hidradenitis suppurativa are emerging, but more research is needed.
    The review discussed advances in understanding and managing hidradenitis suppurativa (HS), a chronic inflammatory skin disease affecting hair follicles, emphasizing its significant impact on quality of life and the complexity of its pathogenesis. It highlighted the need for a multidisciplinary approach, noting differences in disease characteristics across genders and ethnic groups. Emerging therapies were being developed, but more randomized controlled trials on dietary factors and improved outcome measures were needed. The review also addressed the lack of standardized guidelines for managing HS during pregnancy and called for more diverse representation in clinical trials. It underscored the importance of considering diet and weight loss in HS management, with some patients reporting improvements after dietary changes. Additionally, the document noted significant delays in HS diagnosis and the importance of specialized care, including surgery for advanced cases and the use of adalimumab during the COVID-19 pandemic. The complexity of HS management necessitated comprehensive, patient-centered care.
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