Adrenocortical Tumor in a 20-Month-Old Female

October 2008 in “ DOAJ (DOAJ: Directory of Open Access Journals) ”

Mohammad Reza Darabi Mahboob (MD), Alireza Delijani (MD), Mohammad Reza Darabi Mahboob (MD), Alireza Delijani (MD)

adrenocortical tumor virilizing tumor testosterone androstenedione progesterone dehydroepiandrosterone adrenal mass adrenalectomy adrenal carcinoma DHEA

TLDR A 20-month-old girl had a rare adrenal tumor removed successfully, with no recurrence for 10 years.

Adrenocortical virilizing tumors were rare in the pediatric age group, with a 1% incidence for adrenal cancer. This case report described a 20-month-old female who presented with signs of virilization, including increased bone mass and pubic hair growth. Laboratory tests revealed elevated levels of testosterone, androstenedione, progesterone, and a very high level of dehydroepiandrosterone. A CT scan identified a right adrenal mass larger than 5 cm. The patient underwent open surgical adrenalectomy via a lumbar incision, and the pathological examination confirmed adrenal carcinoma. The patient was discharged 5 days post-operation and followed up for 10 years without any pathological lesions.

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