Male Senescence Phenotypes Include Hair Loss and Hair Gain

    August 2026 in “ Cureus ”
    Colleen Reisz, An‐Lin Cheng
    Studysummary This study found that higher scores of hair loss on the Hamilton-Norwood scale correlated with increased hair gain in the conchal bowl in men, suggesting potential age-related adaptations beyond cosmetic concerns.
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    Research cited in this study 10

    1. Modeling Human Hair Follicles: Lessons from Animal Models and Beyond Biology · 2024
    2. Mechanical Stimulation of Human Hair Follicle Outer Root Sheath Cultures Activates Adjacent Sensory Neurons Science advances · 2023
    3. Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis Frontiers in Cell and Developmental Biology · 2022
    4. The Roles of Non-Coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives Frontiers in Cell and Developmental Biology · 2021
    5. The Inflammatory Aspect of Male and Female Pattern Hair Loss Journal of Inflammation Research · 2020
    6. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
    7. Hunting the Genes in Male-Pattern Alopecia: How Important Are They, How Close Are We and What Will They Tell Us? Experimental Dermatology · 2016
    8. Classifications of Patterned Hair Loss: A Review Journal of Cutaneous and Aesthetic Surgery · 2016
    9. Prediction of Male-Pattern Baldness from Genotypes European Journal of Human Genetics · 2015
    10. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009