Clinical, Histopathological and Immunological Characteristics of Exfoliative Cutaneous Lupus Erythematosus in 25 German Short-Haired Pointers
August 2005
in “
Veterinary dermatology
”
exfoliative cutaneous lupus erythematosus alopecia hyperkeratosis lymphocytic interface dermatitis IgG deposition epidermal basement membrane follicular basement membrane antifollicular antibodies antisebaceous gland antibodies immunosuppressive therapy ECLE hair loss skin thickening immune response
Studysummary This study demonstrates that exfoliative cutaneous lupus erythematosus in German short-haired pointers involves a cellular and humoral immune response against the epidermal basement membrane, with poor response to immunosuppressive therapy.
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