Epidermal Growth Factor Promotes Mesenchymal Stem Cell-Mediated Wound Healing and Hair Follicle Regeneration

    January 2017 in “ PubMed ”
    Ying Xia, Xiao-en You, Hong Chen … Shi-Zhang Ding
    Studysummary This study found that adding epidermal growth factor to mesenchymal stem cells enhanced wound healing and hair follicle regeneration in rats compared to stem cells alone.
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    Research cited in this study 12

    1. Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors Stem Cells Translational Medicine · 2016
    2. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    3. Recent Advances in the Epidermal Growth Factor Receptor/Ligand System Biology on Skin Homeostasis and Keratinocyte Stem Cell Regulation Journal of Dermatological Science · 2013
    4. Activin B Promotes BMSC-Mediated Cutaneous Wound Healing by Regulating Cell Migration via the JNK-ERK Signaling Pathway Cell Transplantation · 2013
    5. Transplantation of Bone-Marrow-Derived Mesenchymal and Epidermal Stem Cells Contribute to Wound Healing with Different Regenerative Features Cell and Tissue Research · 2013
    6. Hair Organ Regeneration Via Bioengineered Hair Follicular Unit Transplantation Scientific Reports · 2012
    7. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    8. Clinically Applicable Transplantation Procedure of Dermal Papilla Cells for Hair Follicle Regeneration Journal of Tissue Engineering and Regenerative Medicine · 2011
    9. Adult Bone-Marrow-Derived Mesenchymal Stem Cells Contribute to Wound Healing of Skin Appendages Cell and Tissue Research · 2006
    10. New Aspects of Galectin Functionality in Nuclei of Cultured Bone Marrow Stromal and Epidermal Cells: Biotinylated Galectins as a Tool to Detect Specific Binding Sites Biology of the Cell · 2003
    11. Hair Cycle-Dependent Expression of Hepatocyte Growth Factor Activator, Other Proteinases, and Proteinase Inhibitors Correlates with the Expression of Hepatocyte Growth Factor in Rat Hair Follicles Journal of Investigative Dermatology Symposium Proceedings · 1999
    12. Local Injection of Hepatocyte Growth Factor/Scatter Factor Alters Cyclic Growth of Murine Hair Follicles Journal of Investigative Dermatology · 1998

    Related research 4

    1. Understanding the Functional Contribution of Dermal Stem Cells to Hair Follicle Regeneration and Skin Wound Healing 2017
    2. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015
    3. Epithelial Stem Cells And Implications For Wound Repair Seminars in Cell & Developmental Biology · 2012
    4. Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing PLOS ONE · 2012