Effect of Prostaglandin D2 on Hair Follicle Growth and Its Impact on Hair Follicle Stem/Progenitor Cells
April 2016
in “
Journal of Investigative Dermatology
”
Prostaglandin D2 PGD2 PTGDR2 antagonists androgenetic alopecia keratinocyte proliferation hair follicle stem cells hair follicle progenitor cells apoptosis hair growth phase hair shedding phase male pattern baldness keratinocyte growth hair stem cells hair progenitor cells cell death anagen phase telogen phase
Studysummary This study identified that blocking the PTGDR2 receptor in human hair follicles in vitro and in mice reversed the hair growth inhibition caused by PGD2, suggesting a potential approach for treating alopecia.
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