Comparison of Trichoscopic Features of Alopecia Areata Before and After Treatment with Intralesional Steroids

March 2025 in “ Pakistan Journal of Health Sciences ”

Shahana Hoor, Zahid Rafiq, Syed Ahmad Ali Gardezi, Humaira Kousar

Alopecia Areata intralesional steroids trichoscopy triamcinolone acetate SALT Score black dots exclamation mark hairs yellow dots short vellus hair circle hair steroid injections trichoscopic examination

Studysummary In this study, patients with Alopecia Areata showed significant clinical improvement after intralesional steroid treatment, as trichoscopic features like black dots and exclamation mark hairs decreased, while short vellus and circle hairs increased, highlighting Trichoscopy's utility in monitoring treatment response.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This study evaluated the effectiveness of intralesional steroids in treating Alopecia Areata by comparing trichoscopic features before and after treatment in patients aged 18 to 60 with a SALT Score of less than 50. After 12 weeks of treatment with intralesional triamcinolone acetate, there was a significant reduction in the mean SALT Score from 9.91 to 4.94. Trichoscopic features such as black dots, exclamation mark hairs, and yellow dots decreased significantly, while the presence of short vellus hair and circle hair increased. The study concludes that Trichoscopy is a valuable tool for monitoring therapeutic response in Alopecia Areata, as it effectively demonstrates clinical improvement through changes in these features.

View this study on thejas.com.pk →

Discuss this study in the Community →

Research cited in this study

15 / 15 results

research Alopecia Areata: Understanding the Pathophysiology and Advancements in Treatment Modalities

January 2025 in “Cureus”

This review highlights that alopecia areata is influenced by genetic, autoimmune, and environmental factors, with emerging treatments like JAK-2 inhibitors showing promise for severe cases.

research Assessment of Clinician-Reported Outcome Measures for Alopecia Areata: A Systematic Scoping Review

8 citations , August 2024 in “Clinical and Experimental Dermatology”

This review discusses the limitations of existing clinician-reported outcome measures for alopecia areata and emphasizes the need for a composite scoring system to better assess disease severity.

research The Dermatoscope in the Hair Clinic: Trichoscopy of Scarring and Nonscarring Alopecia

24 citations , August 2023 in “Journal of the American Academy of Dermatology”

Trichoscopy helps diagnose and manage different types of hair loss effectively.

Comparison of Clinical Efficacy and Trichoscopic Changes in Scalp Alopecia Areata Following Treatment with Intralesional Triamcinolone Acetonide and Autologous Platelet-Rich Plasma

research Comparison of Clinical Efficacy and Trichoscopic Changes in Scalp Alopecia Areata Following Treatment with Intralesional Triamcinolone Acetonide and Autologous Platelet-Rich Plasma

July 2023 in “Clinical dermatology review”

This study found that intralesional triamcinolone acetonide is more effective and faster than platelet-rich plasma in promoting hair regrowth for scalp alopecia areata.

research Non-Invasive Techniques for Evaluating Alopecia Areata

June 2023 in “Mædica”

This review discusses various non-invasive methods for diagnosing alopecia areata, highlighting that trichoscopy signs like short vellus hairs and yellow dots are sensitive indicators of the condition, while advanced imaging techniques provide valuable information on hair follicle status and scalp inflammation.

research Utility of Trichoscopy in Comparison to Standard Methods for Assessing Disease Activity, Severity, and Therapeutic Response in Alopecia Areata

1 citations , June 2023 in “Cosmoderma”

This study found that in patients with alopecia areata, trichoscopy was a valuable tool for monitoring disease activity, severity, and therapeutic response, showing changes in trichoscopic markers that preceded improvements observed in the hair pull test.

research Trichoscopy Patterns in Alopecia Areata: A Systematic Review and Meta-Analysis

2 citations , June 2023 in “Skin Research and Technology”

This study reviewed 39 studies with 3204 patients to identify characteristic trichoscopic findings in alopecia areata, highlighting yellow and black dots, broken, short vellus, and tapering hairs as key indicators. It found no single diagnostic trichoscopic finding but observed trichoscopy's utility in monitoring treatment response.

research Microneedling With Triamcinolone Acetonide Versus Intralesional Triamcinolone Acetonide in Treatment of Alopecia Areata

February 2023

This study observed that both intralesional triamcinolone acetonide and microneedling with triamcinolone acetonide significantly reduced alopecia areata severity, with no significant difference in effectiveness between the two treatments, suggesting microneedling as an effective and less invasive option.

research Trichoscopy in Alopecia Areata

7 citations , November 2022 in “Actas Dermo-Sifiliográficas”

This study reviewed the usefulness of trichoscopy in diagnosing and monitoring alopecia areata, noting that the technique identifies specific hair features like yellow and black dots, which are linked to the disease's chronic nature and treatment response.

research Trichoscopy as an Evaluation Method for Alopecia Areata Treatment: A Comparative Study

12 citations , September 2020 in “Journal of cosmetic dermatology”

This study found that trichoscopy aided in assessing treatment responses for patchy alopecia areata, with both intralesional corticosteroids and platelet-rich plasma showing effectiveness, but only PRP significantly improved patient symptom impact scores.

research Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata

134 citations , July 2020 in “Experimental dermatology”

This review discusses immune privilege in anagen hair follicles and its collapse in alopecia areata, emphasizing the importance of restoring this function for effective management and disease relapse prevention.

research Alopecia Areata: A Multifactorial Autoimmune Condition

148 citations , December 2018 in “Journal of autoimmunity”

This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.

research Trichoscopy of Alopecia Areata: An Update

89 citations , March 2018 in “The Journal of Dermatology”

This review presents various trichoscopic findings for diagnosing alopecia areata but reports no new clinical results, emphasizing that no single marker is pathognomonic and multiple features should be considered together.

research Scalp Dermoscopy or Trichoscopy

69 citations , January 2015 in “Current problems in dermatology”

This review discusses trichoscopy as a noninvasive, effective technique for diagnosing various hair loss conditions and monitoring treatment, highlighting its potential to reduce scalp biopsy necessity.

research Dermoscopic Evaluation of Therapeutic Response to an Intralesional Corticosteroid in the Treatment of Alopecia Areata

35 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

This study found that intralesional triamcinolone acetonide is effective for treating localized patchy alopecia areata, with dermoscopy aiding in early detection of clinical response and adverse effects.