Eyelash Trichomegaly: Review of Congenital, Acquired, and Drug-Associated Etiologies for Elongation of the Eyelashes

May 2012 in “ International Journal of Dermatology ”

L Paul, Philip R. Cohen, Razelle Kurzrock

eyelash trichomegaly congenital acquired drug-associated immune dysfunction syndromes benign familial trait

Studysummary This review discusses the various causes and associations of eyelash trichomegaly, including congenital syndromes, acquired conditions, and drug effects, without reporting new clinical results.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

14 / 14 results

research Cetuximab-Associated Elongation of the Eyelashes

30 citations , August 2010 in “American Journal of Clinical Dermatology”

This article reviews eyelash elongation as a side effect of EGFR inhibitors in cancer treatment, finding that the condition is typically not severe and may be managed by trimming.

research Persistent Hair Growth During Treatment With the EGFR Inhibitor Erlotinib

39 citations , March 2009 in “Dermatology Online Journal”

This review observes that trichomegaly, a newly described side effect of EGFR inhibitors causing excessive eyelash and scalp hair growth, persists in some patients whose tumors respond positively to the therapy.

research Trichomegaly in a 3-Year-Old Girl with Alopecia Areata

15 citations , March 2009 in “Pediatric dermatology”

This case report documents a novel occurrence of bilateral trichomegaly with alopecia areata in a healthy 3-year-old girl, without known underlying health conditions or medication use.

research Non-Rash Skin Toxicities Associated with Novel Targeted Therapies

28 citations , December 2006 in “Clinical lung cancer”

This review outlines various non-rash skin toxicities associated with novel targeted anticancer therapies and provides guidelines for their early diagnosis and management, but reports no new clinical results.

research The PRIDE Syndrome: Dermatological Side Effects of EGFR Inhibitors

90 citations , August 2006 in “British Journal of Dermatology”

This paper describes the PRIDE syndrome associated with epidermal growth factor receptor inhibitors but reports no new clinical results.

research Acquired Trichomegaly with Topiramate

24 citations , July 2005 in “Journal of the American Academy of Dermatology”

In this case report, the authors suggest that topiramate, used for treating bipolar disorder, may cause trichomegaly, or excessive eyelash growth, in patients.

research Trichomegaly of the Eyelashes Following Treatment with Cetuximab

78 citations , June 2005 in “Annals of oncology”

This case study reported that a 74-year-old woman with metastatic rectal cancer experienced temporary trichomegaly, or eyelash lengthening, associated with cetuximab treatment, which resolved after discontinuation of the drug.

research Lash Ptosis Caused by Latanoprost

31 citations , April 2005 in “American journal of ophthalmology”

This case report identified lash ptosis as a potential complication of latanoprost therapy in a 61-year-old man with ocular hypertension.

research Influence of Prostaglandin F2α and Its Analogues on Hair Regrowth and Follicular Melanogenesis in a Murine Model

103 citations , April 2005 in “Experimental dermatology”

This study found that PGF2alpha analogues and PGE2 stimulated hair follicle activity in mice, with PGF2alpha analogues also linked to potential side effects like poliosis when used as eye treatments.

research Hypertrichosis of the Eyelashes Caused by Bimatoprost

65 citations , November 2004 in “Journal of the American Academy of Dermatology”

This article reports a case where the IOP-lowering drug bimatoprost was associated with eyelash hypertrichosis.

research Eyelash Length in Children and Adolescents with Allergic Diseases

16 citations , September 2004 in “Pediatric dermatology”

This study found that children and adolescents with allergic diseases have significantly longer eyelashes compared to nonallergic controls.

research Hypertrichosis

125 citations , February 2003 in “Journal of the American Academy of Dermatology”

This review discusses various forms and categories of hypertrichosis, as well as methods for managing the condition, but does not report new clinical results.

research Hypertrichosis Induced by Latanoprost

39 citations , April 2001 in “Journal of The American Academy of Dermatology”

This article reviews the side effects of topical latanoprost therapy, particularly the hypertrichosis and pigmentation changes of eyelashes and nearby skin, and reports no new clinical results.

Hypertrichosis and Increased Pigmentation of Eyelashes and Adjacent Hair in the Region of the Ipsilateral Eyelids of Patients Treated with Unilateral Topical Latanoprost

research Hypertrichosis and Increased Pigmentation of Eyelashes and Adjacent Hair in the Region of the Ipsilateral Eyelids of Patients Treated with Unilateral Topical Latanoprost

216 citations , October 1997 in “American Journal of Ophthalmology”

This study found that unilateral topical latanoprost use for glaucoma was associated with hypertrichosis and increased pigmentation of eyelashes in the treated eye compared to the untreated eye.