Preservation of Stem Cells in Androgenetic Alopecia

October 2017 in “ Journal of The European Academy of Dermatology and Venereology ”

Hend Gamil, Magda Assaf, Mohamed A. Elsayed, K. Gharib, Mohamed Y. Soliman, N.A. Mostafa

androgenetic alopecia follicular stem cells bulge region CD34+ cells progenitor cells follicular miniaturization AGA stem cells

Studysummary Stem cells preservation in AGA could be a potential therapy, but more cases needed.

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Research cited in this study

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research Stem Cells and the Skin

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This review outlines the processes and potential of stem cells in regenerating skin, hair, and other tissues but presents no new experimental findings.

research Stem Cells and Alopecia: A Review of Pathogenesis

33 citations , April 2012 in “British Journal of Dermatology”

This review discusses the role of stem cells in alopecia pathogenesis, highlighting the differences between scarring and nonscarring types, and reports no new clinical results.

research Guidelines for the Management of Androgenetic Alopecia (2010)

38 citations , December 2011 in “Journal of Dermatology”

This article reviews current guidelines for managing androgenetic alopecia and highlights the need for guidelines tailored to Japan; it reports no new clinical results.

Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells

research Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells

235 citations , January 2011 in “Journal of Clinical Investigation”

This study found that androgenetic alopecia may involve a defect in the conversion of hair follicle stem cells to progenitor cells, as demonstrated by a reduced presence of progenitor cells in bald scalp samples.

research Stem Cell Markers (Cytokeratin 15, CD34, and Nestin) in Primary Scarring and Nonscarring Alopecia

54 citations , January 2009 in “British Journal of Dermatology”

This study found that in scarring alopecia, stem cells are differentially localized, suggesting that both inner and outer root sheath stem cells, rather than just follicular bulge stem cells, are involved.

research Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis

1279 citations , November 2005 in “Nature Medicine”

research Pathobiology of Androgenetic Alopecia

5 citations , November 2003 in “Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic”

This review explores the key factors influencing hair growth implicated in androgenetic alopecia and reports no new clinical findings.