Micropatterned Dermal–Epidermal Regeneration Matrices Create Functional Niches That Enhance Epidermal Morphogenesis
August 2013
in “
Acta Biomaterialia
”
micropatterned dermal–epidermal regeneration matrix μDERM epidermal morphogenesis keratinocyte function keratinocyte niches proliferative niches basement membrane protein synthesis putative stem cell niches epidermal thickness keratinocyte proliferation laminin-332 β1brip63+ keratinocytes skin regeneration graft performance skin substitutes in vitro skin research skin regeneration matrix skin grafts lab-grown skin
Studysummary This study suggests that a novel micropatterned dermal–epidermal matrix (μDERM) enhances keratinocyte function and epidermal morphology, offering potential improvements in skin substitute design for wound healing applications.
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