Hair Grows Hair: Dual-Effective Hair Regrowth Through a Hair Enhanced Dissolvable Microneedle Patch Cooperated with Pure Yellow Light Irradiation

October 2021 in “ Applied materials today ”

Can Hong, Guoliang Zhang, Wei Zhang, Jiaqi Liu, Jiao Zhang, Yutong Chen, Haichuan Peng, Yuan Cheng, Xingwei Ding, Hong‐Bo Xin, Xiaolei Wang

dissolvable microneedle patches exosomes human amniotic mesenchymal stem cells hair nanoparticles hair follicle stem cells yellow light irradiation inflammation reduction hair regrowth HMNs hAMSCs HNPs

Studysummary This study demonstrated that a new technology combining microneedle patches, stem cell exosomes, and light therapy effectively promoted hair regrowth in animal models within 7 days compared to conventional treatments.

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research Platelet-Rich Plasma Has a Place in the Treatment of Androgenetic Alopecia

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research Proposed Mechanisms of Low-Level Light Therapy in the Treatment of Androgenetic Alopecia

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This review suggests that low-level light therapy can promote hair growth in patients with androgenetic alopecia, but more research is needed to standardize treatment parameters and assess long-term safety and efficacy.

research Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling

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research Low-Level Laser Therapy and Narrative Review of Other Treatment Modalities in Androgenetic Alopecia

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LLLT is a safe, promising hair loss treatment, but more research needed.

research Sustained Release of Dermal Papilla-Derived Extracellular Vesicles from Injectable Microgel Promotes Hair Growth

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This study demonstrated that OSA hydrogels enhanced the stability and retention of dermal papilla-derived extracellular vesicles, which significantly improved hair regeneration in both cultured human hair and a mouse depilation model.

research Co-Loading of Finasteride and Baicalin in Phospholipid Vesicles Tailored for the Treatment of Hair Disorders

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research Self-Activated Electrical Stimulation for Effective Hair Regeneration via a Wearable Omnidirectional Pulse Generator

92 citations , September 2019 in “ACS nano”

This study observed that a wearable electric stimulation device significantly promoted hair regeneration in rats and mice, outperforming conventional pharmacological treatments and enhancing growth factor secretion.

research Priming Mobilization of Hair Follicle Stem Cells Triggers Permanent Loss of Regeneration After Alkylating Chemotherapy

32 citations , August 2019 in “Nature Communications”

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research Several Biological Benefits Of The Low Color Temperature Light-Emitting Diodes Based Normal Indoor Lighting Source

45 citations , May 2019 in “Scientific Reports”

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research Mechanical Stretch Induces Hair Regeneration Through the Alternative Activation of Macrophages

163 citations , April 2019 in “Nature Communications”

This study found that mechanical skin stretching can stimulate hair stem cell proliferation and hair regeneration by activating a complex pathway involving WNT, BMP-2, and M2 macrophages.

research A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth

192 citations , April 2019 in “ACS nano”

In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.

research Reactive Keratin Derivatives: A Promising Strategy for Covalent Binding to Hair

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This study found that keratin derivatives with functionalized thiol groups improved binding to both natural and bleached hair fibers, suggesting a promising strategy for enhancing keratin's durability in hair repair.

research Low-Level Laser Therapy for the Treatment of Androgenic Alopecia: A Review

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Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice

research Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice

113 citations , November 2017 in “Scientific Reports”

This study found that treatment with mesenchymal stem cell extracellular vesicles enhanced hair growth in mice and stimulated dermal papilla cell activity and growth factor production in vitro.

research Spontaneous Hair Follicle Germ Formation In Vitro, Enabling The Large-Scale Production Of HFGs For Regenerative Medicine

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research Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type

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This study identifies a bipotent stem cell in adult hair follicles that self-renews and contributes to dermal sheath and papilla cell populations, potentially aiding hair regrowth after injury, disease, or aging.

research Stem Cells and Alopecia: A Review of Pathogenesis

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This review discusses the role of stem cells in alopecia pathogenesis, highlighting the differences between scarring and nonscarring types, and reports no new clinical results.

research Evaluation and Treatment of Male and Female Pattern Hair Loss

203 citations , December 2004 in “Journal of The American Academy of Dermatology”

This article reviews the historical developments in understanding and treating male pattern hair loss, emphasizing the role of dihydrotestosterone and 5α-reductase inhibitors, but reports no new clinical findings.