Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators

November 2014 in “ PLOS Computational Biology ”

Ryan Tasseff, Anjali Bheda-Malge, Teresa DiColandrea, Charles C. Bascom, Robert J. Isfort, Richard Gelinas

hair cycle gene expression epithelial cells mesenchymal cells hair miniaturization RNA imaging protein imaging follicular epithelial cells hair growth gene clusters

Studysummary In this study, researchers found that synchronization between expanding epithelial cells and background mesenchymal cells in the mouse hair cycle may be maintained by inhibitory regulation, with potential mediators of this regulation identified.

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