Mesenchymal Stem Cells And Their Secretome: A Promising Approach For Parkinson’s Disease Treatment

    June 2026 in “ The Egyptian Journal of Neurology Psychiatry and Neurosurgery ”
    Shayan Zanjaniha, Haniyeh Moradi, Paria Zahedi … Davod Jafari
    Studysummary This review discusses the potential of mesenchymal stem cells and their secretome, mainly extracellular vesicles, in Parkinson's disease therapy, highlighting their neuroprotective abilities and therapeutic prospects, but it reports no clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 5

    1. Mir-574-3p and Mir-125a-5p in Adipose-Derived Mesenchymal Stem Cell Exosomes Synergistically Target TGF-β1/Smad2 Signaling Pathway for the Treatment of Androgenic Alopecia Journal of Investigative Dermatology · 2025
    2. Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway International Journal of Molecular Sciences · 2023
    3. Mesenchymal Stem Cells for Regenerative Medicine Cells · 2019
    4. Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine International Journal of Molecular Sciences · 2017
    5. Stem Cells Applications In Regenerative Medicine And Disease Therapeutics International Journal of Cell Biology · 2016