Simultaneous Determination of Multi-Class Active Pharmaceutical Ingredients by UHPLC-HRMS
May 2021
in “
Journal of pharmaceutical and biomedical analysis
”
UHPLC-HRMS quadrupole-orbitrap mass spectrometer active pharmaceutical ingredients acne hair loss male erectile dysfunction skin whitening ultrasound-assisted extraction high-resolution product ion spectral library collision energies HRMS2 spectra stable isotopically labeled API analogs internal standards instrument quality control high-resolution mass spectrometry API UAE HRMS2 isotopically labeled standards quality control
Studysummary This study utilized a UHPLC-HRMS method to identify eight active pharmaceutical ingredients, such as ketoconazole and minoxidil, in 26 out of 100 analyzed cosmetic products.
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