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GlossaryInternal Standard

substance added to samples to ensure accurate measurements

An Internal Standard (IS) is a substance added in a constant amount to samples, calibrators, and quality controls in an analytical experiment. It is used to correct for variations in sample preparation and instrument response, ensuring more accurate and consistent results. This technique is particularly useful in fields like biochemistry and pharmacology, where precise quantification of compounds is critical.

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research Matrix Matching in Quantitative Bioanalysis by LC-MS/MS: A Dream or a Reality?

2 citations, December 2019 in “Bioanalysis”

Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.

research Simultaneous Determination of Multi-Class Active Pharmaceutical Ingredients by UHPLC-HRMS

2 citations, May 2021 in “Journal of pharmaceutical and biomedical analysis”

A new method was developed to accurately detect and measure 47 different drug ingredients in various products.

research Matrix Effects And Application Of Matrix Effect Factor

323 citations, November 2017 in “Bioanalysis”

Matrix effects in LC-MS can be managed but not completely avoided.

Quantitative Analysis of Finasteride Tablets Dissolution Content with Non-Isotopically Labeled Internal Standard by Paper Spray Ionization Mass Spectrometry

research Quantitative Analysis of Finasteride Tablets Dissolution Content with Non-Isotopically Labeled Internal Standard by Paper Spray Ionization Mass Spectrometry

2 citations, September 2018 in “Journal of Separation Science”

PSI-MS quickly and accurately measures finasteride in tablets, helping with quality control.

research High-Performance Liquid Chromatographic Determination of α-Tocopheryl Nicotinate in Cosmetic Preparations

5 citations, February 1992 in “Journal of chromatography A/Journal of chromatography”

The document concludes that a fast, accurate method to measure vitamin E derivative in cosmetics was developed.

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community Anagenic announces the launch Pyrilutamide on their website. Are you excited ?

in Treatment 80 upvotes 2 years ago

The launch of Pyrilutamide as a potential hair loss treatment, with people discussing whether it is better than treatments like finasteride and minoxidil. Some participants have also discussed the risks associated with importing drugs from China.

community People treat me so different when I was bald compared to my comb over.

in Chat 226 upvotes 1 month ago

The user feels treated better with a comb-over than when bald due to cancer. They are considering a hair transplant and using finasteride and minoxidil for hair loss.

community This sub is very toxic towards people who don’t blindly follow the fin mafia

in Treatment 226 upvotes 1 year ago

The conversation criticizes the negative attitude towards those concerned about side effects from hair loss treatments like finasteride and minoxidil, or who prefer natural remedies. Specific treatments discussed include finasteride, minoxidil, rosemary oil, and RU58841, with an agreement that finasteride and minoxidil are proven effective.

community Got my first hair system put on yesterday. I feel like a brand new man. Haven’t been confident in so many years.

in Hair Systems 385 upvotes 3 years ago

User got first hair system and feels confident. Cost $200, attached at hairclub for $150, considering $400 monthly membership for weekly visits and new system monthly.

community Girl found my toppik

in Chat 221 upvotes 4 years ago

Girl finds guy's hair building fibers, sparking discussion on hair's role in attraction and self-esteem. Treatments like Minoxidil, finasteride, and hair systems are mentioned.

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