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GlossaryQTc interval

time for heart's electrical system to recharge, adjusted for rate

The QTc interval, or Corrected QT interval, is a measurement on an electrocardiogram (ECG) that represents the time it takes for the heart's electrical system to recharge between beats, adjusted for heart rate. It is important because a prolonged QTc interval can indicate an increased risk of life-threatening arrhythmias, such as Torsades de Pointes.

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A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity

research A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity

2 citations, May 2021 in “Clinical Pharmacology in Drug Development”

Clascoterone is safe for the heart, even at high doses.

Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study

research Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study

17 citations, August 2019 in “Archives of Cardiovascular Diseases”

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

research Impact of Medical Castration on Malignant Arrhythmias in Patients With Prostate Cancer

8 citations, February 2021 in “Journal of the American Heart Association”

Medical castration in prostate cancer patients can increase the risk of serious heart rhythm problems, so it's important to monitor heart activity during treatment.

research Reporting on Adverse Clinical Events

November 2015 in “Clin-Alert”

Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.

research Eosinophilia Associated with Clozapine – A Case Report

1 citations, April 2017 in “European Psychiatry”

A patient's allergic reaction to clozapine resolved without stopping the medication, showing the importance of blood monitoring.

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