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GlossaryInternal Standard

substance added to samples to ensure accurate measurements

An Internal Standard (IS) is a substance added in a constant amount to samples, calibrators, and quality controls in an analytical experiment. It is used to correct for variations in sample preparation and instrument response, ensuring more accurate and consistent results. This technique is particularly useful in fields like biochemistry and pharmacology, where precise quantification of compounds is critical.

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Quantitative Analysis of Finasteride Tablets Dissolution Content with Non-Isotopically Labeled Internal Standard by Paper Spray Ionization Mass Spectrometry

research Quantitative Analysis of Finasteride Tablets Dissolution Content with Non-Isotopically Labeled Internal Standard by Paper Spray Ionization Mass Spectrometry

2 citations, September 2018 in “Journal of Separation Science”

PSI-MS quickly and accurately measures finasteride in tablets, helping with quality control.

research Matrix Matching in Quantitative Bioanalysis by LC-MS/MS: A Dream or a Reality?

2 citations, December 2019 in “Bioanalysis”

Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.

research Metal Doped Keratin Film Standard for LA-ICP-MS Determination of Lead in Hair Samples

18 citations, December 2010 in “Journal of analytical atomic spectrometry”

A new method accurately measures lead levels in hair to assess exposure.

research Simultaneous Determination of Multi-Class Active Pharmaceutical Ingredients by UHPLC-HRMS

2 citations, May 2021 in “Journal of pharmaceutical and biomedical analysis”

A new method was developed to accurately detect and measure 47 different drug ingredients in various products.

Ultra-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Ketoconazole in Anti-Dandruff Shampoo

research Ultra-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Ketoconazole in Anti-Dandruff Shampoo

1 citations, February 2014 in “Analytical Letters”

The method accurately measures the amount of ketoconazole in anti-dandruff shampoo and cream, and can also be used to monitor the drug in human plasma.

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community Is there a consensus on RU these days? Pyril turned out to be a bust right?

in Research/Science 17 upvotes 9 months ago

The conversation discusses the effectiveness and safety of hair loss treatments, specifically RU58841 and Pyrilutimide (Pyril), with users sharing that Pyril was no more effective than a placebo and expressing concerns about the safety of RU58841 based on personal experiences and the lack of pharmaceutical interest.

community Front page article at The New York Times (biggest circulation in the world) regarding notable results with oral minoxidil is a pretty big deal

in Minoxidil 2 years ago

This conversation discusses the potential benefits of using oral minoxidil and finasteride to treat hair loss, with some users sharing their own experiences in taking the medications. Others express concerns about the safety of these treatments.

community My Dermatologist is bald. Yall think he’ll prescribe me Fin or be a hater and want to see me bald too?

in Chat 467 upvotes 1 month ago

Concerns about hair loss treatments, specifically finasteride and minoxidil, and doubts about a bald dermatologist prescribing them. Users recommend finding a dermatologist who prescribes effective treatments or exploring online options for finasteride.

community Anagenic announces the launch Pyrilutamide on their website. Are you excited ?

in Treatment 80 upvotes 2 years ago

The launch of Pyrilutamide as a potential hair loss treatment, with people discussing whether it is better than treatments like finasteride and minoxidil. Some participants have also discussed the risks associated with importing drugs from China.

community Just find a cure already, I am totally done

in Chat 161 upvotes 3 months ago

The conversation is about hair loss treatments, with users recommending finasteride and minoxidil as effective solutions. Some users report side effects, but overall, the consensus is to use these treatments rather than waiting for a cure.

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