2 citations,
December 2019 in “Bioanalysis” Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.
2 citations,
May 2021 in “Journal of pharmaceutical and biomedical analysis” A new method was developed to accurately detect and measure 47 different drug ingredients in various products.
323 citations,
November 2017 in “Bioanalysis” Matrix effects in LC-MS can be managed but not completely avoided.
2 citations,
September 2018 in “Journal of Separation Science” PSI-MS quickly and accurately measures finasteride in tablets, helping with quality control.
5 citations,
February 1992 in “Journal of chromatography A/Journal of chromatography” The document concludes that a fast, accurate method to measure vitamin E derivative in cosmetics was developed.
823 citations,
February 1998 in “Analytical Chemistry” Method detects finasteride in plasma at very low concentrations.
51 citations,
February 2010 in “Analytical and Bioanalytical Chemistry” Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.
14 citations,
May 2005 in “Farmaco” A method was created in 2005 to identify minoxidil, a hair growth ingredient, in products using two types of capillary zone electrophoresis, and it found that most products had about 2% minoxidil.
12 citations,
March 2018 in “Analytical chemistry” Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.
8 citations,
October 2014 in “Journal of analytical toxicology.” Chemical hair straightening significantly reduces detectable drug levels in hair.
82 citations,
January 2002 in “Journal of drug targeting” Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.
46 citations,
January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
18 citations,
June 2010 in “Journal of Chromatography B” New method measures finasteride in blood quickly and accurately.
1 citations,
April 2015 in “Drug research” New method measures finasteride in plasma, finds two formulations bioequivalent.
1 citations,
August 2006 in “International forensic science and investigation series” Hair testing is a reliable method for detecting workplace drug use when done with proper sample preparation and confirmation.
Forensic hair analysis for drugs is now more reliable and accurate.
128 citations,
January 1996 in “Journal of analytical toxicology.” Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.
96 citations,
September 2017 in “Analytica Chimica Acta” Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.
71 citations,
January 2014 in “Journal of Proteome Research” Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.
61 citations,
April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
59 citations,
November 2018 in “Psychoneuroendocrinology” Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
59 citations,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
58 citations,
April 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
55 citations,
March 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
52 citations,
June 2013 in “The Journal of Clinical Endocrinology and Metabolism” The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.
49 citations,
December 2017 in “Journal of pharmaceutical and biomedical analysis” The method effectively detects banned substances in urine for sports antidoping.
47 citations,
January 2001 in “Journal of Investigative Dermatology” High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.
46 citations,
May 2012 in “Molecular and Cellular Endocrinology” Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
40 citations,
June 2011 in “Journal of biological chemistry/The Journal of biological chemistry” FA2H is essential for normal fur and sebum production in mice.
39 citations,
April 2007 in “Therapeutic Drug Monitoring” Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.