Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands

    Peter W. Jurutka, Leonid Bartik, G. Kerr Whitfield … Mark R. Haussler
    Studysummary This study suggests that 1,25-dihydroxyvitamin D(3) and fibroblast growth factor 23 form a crucial axis in regulating phosphate balance, akin to its role in calcium regulation, and explores novel VDR interactions including with curcumin.
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    Research cited in this study 5

    1. Cloning of a Functional Vitamin D Receptor from the Lamprey, an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth Endocrinology · 2003
    2. Targeting Expression of the Human Vitamin D Receptor to the Keratinocytes of Vitamin D Receptor Null Mice Prevents Alopecia Endocrinology · 2001
    3. The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed Journal of bone and mineral research · 1998
    4. Pure Linoleate Deficiency in the Rat: Influence on Growth, Accumulation of N-6 Polyunsaturates, and [1-14C]Linoleate Oxidation Journal of Lipid Research · 1997
    5. Human Essential Fatty Acid Deficiency Archives of Dermatology · 1977