Combining 675 Nm Laser with Isotretinoin for Enhanced Acne Vulgaris Treatment Outcomes

November 2025 in “ Healthcare ”

Ariel Haus, Alessandro Clementi, Giovanni Cannarozzo, Luca Guarino, Elena Zappia, Marco Gratteri, Annunziata Dattola, Steven Paul Nisticò

isotretinoin 675 nm red-light laser acne vulgaris Acne Radar Questionnaire Global Evaluation Acne scale Accutane red-light therapy

Studysummary This study found that among young patients with acne vulgaris, combining a 675 nm red-light laser with isotretinoin led to more rapid and pronounced improvement in lesion severity compared to laser treatment alone, without adverse events. Our plain-language summary of this paper — not a Tressless recommendation.

The study evaluated the effectiveness of combining a 675 nm laser with isotretinoin for treating acne vulgaris in 13 young patients, divided into two groups: one receiving only laser treatment (7 patients) and the other receiving both laser and isotretinoin (6 patients). Both groups showed significant improvements in acne severity, but the combination therapy group experienced more rapid and pronounced improvements. The treatment was well-tolerated, with no adverse events reported. The study concludes that the 675 nm laser is a safe and effective treatment for acne vulgaris, with enhanced outcomes when combined with isotretinoin. However, the small sample size and short follow-up period limit the findings, suggesting a need for further research.

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6 / 6 results

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