Combining 675 Nm Laser with Isotretinoin for Enhanced Acne Vulgaris Treatment Outcomes

    November 2025 in “ Healthcare
    Ariel Haus, Alessandro Clementi, Giovanni Cannarozzo, Luca Guarino, Elena Zappia, Marco Gratteri, Annunziata Dattola, Steven Paul Nisticò
    TLDR Combining a 675 nm laser with isotretinoin improves acne treatment results.
    The study evaluated the effectiveness of combining a 675 nm laser with isotretinoin for treating acne vulgaris in 13 young patients, divided into two groups: one receiving only laser treatment (7 patients) and the other receiving both laser and isotretinoin (6 patients). Both groups showed significant improvements in acne severity, but the combination therapy group experienced more rapid and pronounced improvements. The treatment was well-tolerated, with no adverse events reported. The study concludes that the 675 nm laser is a safe and effective treatment for acne vulgaris, with enhanced outcomes when combined with isotretinoin. However, the small sample size and short follow-up period limit the findings, suggesting a need for further research.
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