Class IIa HDAC4 and HDAC7 Cooperatively Regulate Gene Transcription in Th17 Cell Differentiation

    April 2024 in “ Proceedings of the National Academy of Sciences ”
    Ka Lung Cheung, Li Zhao, Rajal Sharma … Ming‐Ming Zhou
    Studysummary This study found that selectively targeting HDAC4 and HDAC7 in mice can reduce Th17 cell-mediated intestinal inflammation, suggesting a potential treatment approach for Th17-related inflammatory diseases like ulcerative colitis.
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